The Passage, by Justin Cronin

Science, vampires, apocolypse... fantastic. Not exactly the review you would expect from me on a sci-fi novel. But this book was so exciting that I was completely forgiven of my genre departure. The backstories of both the "heros" and the vampire/zombie/whatevers were great - I'm excited to see how the somewhat sympathetic horrible monsters play out. Yes, this is a series. Book 2, The Twelve, comes out in October.